"Neurotoxins" ed. by J. Eric McDuffie

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"Neurotoxins"  ed. by J. Eric McDuffie

"Neurotoxins" ed. by J. Eric McDuffie
ITExLi | 2018 | ISBN: 1789231698 9781789231694 178923168X 9781789231687 | 147 pages | PDF | 14 MB

This volume is dedicated to natural toxins, synthetic molecules, and therapeutic agents. Taken together, the foreseen need to highlight some of the more appreciated and/or emerging tactical approaches in neurotoxicology results in a "one-stop reference" book, Neurotoxins.

Toxicologists seek to better understand the myriad of mechanisms responsible for neurotoxins. Because the incidence of neurobehavioral hazards and risks of exogenous compounds (e.g., natural toxins, synthetic molecules, and therapeutic agents) remain a subject matter of interest, predictive tools have evolved, including but not limited to novel translational in vitro models, biomarkers, newer epidemiological research tools, and well-accepted best practices for diagnosing neurotoxins in clinical practice.

1 Using Human Pluripotent Stem Cell-Derived Neural Cultures to Assess Safety of New Drugs and Chemicals
2 Induced Pluripotent Stem Cell-Derived Human Glutamatergic Neurons as a Platform for Mechanistic Assessment of Inducible Excitotoxicity in Drug Discovery
3 Use of the Model Organism Caenorhabditis elegans to Elucidate Neurotoxic and Behavioral Effects of Commercial Fungicides
4 Neurotoxins and Autism
5 Botulinum Neurotoxin: A Multifunctional Protein for the Development of New Therapeutics
6 Resistance to Botulinum Toxin in Aesthetics
7 Developmental Neurotoxicity of Fluoride: A Quantitative Risk Analysis Toward Establishing a Safe Dose for Children
8 Targeting Acid-Sensing Ion Channels by Peptide Toxins

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